I really like this advice. I haven't felt sore in the gym in a while and that's when I know it’s time to lift HEAVY! I always have high volume in my routine but once i start losing that soreness, I know it's time to shock the muscles and lift till failure.
Like Scott says this is the best time to have a spotter because towards the end you should definitely be failing and yelling at the weight to get it up!
All the comments here are great advice. Good job everyone!